Proton Magnetic Resonance Spectroscopy of the Central Nervous System

Currently, conventional MR imaging (MRI) is considered to be an established and useful tool in brain disease detection and it is widely chosen as the initial examination step in patients suspected of brain lesions as it is effective in simultaneously characterizing the soft tissue, cerebrospinal fluid (CSF) spaces, and blood vessels. It is a flexible imaging modality for which contrast can be extensively manipulated without patient burdening by ionizing radiation. Nevertheless, the accurate characterization of brain lesions with MR imaging remains problematic in several cases as the sensitivity and specificity with which this modality defines several brain lesions remains limited [1].